The Office of Research Integrity

Institutional Biosafety Committee

The Institutional Biosafety Committee (IBC) ensures that research involving recombinant DNA and biological materials follows designated guidelines.  The IBC follows the guidelines established by the National Institutes of Health (NIH) Office of Biotechnology Activities and The Center for Disease Control (CDC). If you have any questions regarding the IBC committee, the best way to contact us is by email at , however,  you may also call 336-256-1482.

The IBC’s working definition of a biohazardous agent includes the following:

  • Pathogenic agents (bacteria, rickettsia, fungi, viruses, protozoa, parasites, prions, and select agents)
  • Recombinant or synthetically derived nucleic acid, including those that are chemically or otherwise modified analogs of nucleotides (e.g., morpholinos), or both. The NIH defines synthetically derived nucleic acid molecules as follows:
  1. Molecules that a) are constructed by joining nucleic acid molecules and b) can replicate in a living cell (i.e., recombinant nucleic acids);
  2. Nucleic acid molecules that are chemically or by other means synthesized or amplified, including those that are chemically or otherwise modified but can base pair with naturally occurring nucleic acid molecules (i.e., synthetic nucleic acids);
  3. Molecules that result from the replication of those described in (a) or (b) above
  • Recombinant DNA molecules, organisms, vectors (e.g., plasmids, viral vectors), and viruses containing recombinant DNA molecules
  • Human and non-human primate blood, tissue, body fluid, and cell culture (primary or continuous)
  • Plants, animals or derived waste which contain or may contain pathogenic hazards (including xenotransplantation tissue)

Institutional Biosafety Committee Forms

Policy and Guidance


Federal Guidance